Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258130 | 0.92 | GRIN1 (0.48) | ALDH1A1TSHREPHX2LMNAMAPK1 | |
| SCHEMBL29258211 | 0.89 | SMN1; SMN2 (0.54) | LMNAMAPK1ROCK2SCN2ASCN10A | |
| SCHEMBL29258277 | 0.85 | SMN1; SMN2 (0.57) | ALDH1A1TSHRLMNAMAPK1ROCK2 | |
| SCHEMBL29258544 | 0.84 | NPC1 (0.57) | MAPK1ROCK2SMN1; SMN2KMT2A | |
| SCHEMBL29258169 | 0.84 | SMN1; SMN2 (0.47) | TSHRLMNAMAPK1ROCK2SMN1; SMN2 | |
| SCHEMBL29258268 | 0.84 | LMNA (0.51) | LMNAMAPK1ROCK2SMN1; SMN2MAPT | |
| SCHEMBL29258251 | 0.82 | HDAC1 (0.47) | ALDH1A1EPHX2LMNAMAPK1ROCK2 | |
| SCHEMBL29258184 | 0.82 | KMT2A (0.53) | ALDH1A1LMNAMAPK1ROCK2SMN1; SMN2 | |
| SCHEMBL29258236 | 0.82 | HDAC3 (0.49) | ALDH1A1LMNAMAPK1ROCK2KMT2A | |
| SCHEMBL29258199 | 0.81 | NAMPT (0.53) | ALDH1A1LMNAMAPK1ROCK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |