Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258310 | 0.92 | HDAC3 (0.49) | HDAC3HDAC1HDAC2NCOR2ROCK2 | |
| SCHEMBL29258199 | 0.89 | NAMPT (0.53) | HDAC3HDAC1HDAC2NCOR2ROCK2 | |
| SCHEMBL29258289 | 0.85 | L3MBTL1 (0.63) | HDAC3HDAC1HDAC2NCOR2ROCK2 | |
| SCHEMBL29258229 | 0.84 | HDAC1 (0.50) | HDAC3HDAC1HDAC2NCOR2ROCK2 | |
| SCHEMBL29258530 | 0.84 | ROCK2 (0.51) | HDAC3HDAC1HDAC2NCOR2ROCK2 | |
| SCHEMBL29258693 | 0.84 | AURKA (0.57) | HDAC3HDAC1HDAC2NCOR2ROCK2 | |
| SCHEMBL29258309 | 0.83 | HTT (0.45) | HDAC3HDAC1HDAC2NCOR2ROCK2 | |
| SCHEMBL29258215 | 0.82 | HDAC1 (0.58) | HDAC1ROCK2LMNAALDH1A1POLB | |
| SCHEMBL29258211 | 0.81 | SMN1; SMN2 (0.54) | ROCK2L3MBTL1LMNAKMT2AMAPK1 | |
| SCHEMBL29258159 | 0.81 | HPGD (0.62) | ROCK2NAMPTLMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |