Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | PRKX | P51817 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258169 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRCYP3A4MAPK14MMP13 | |
| SCHEMBL29258227 | 0.90 | MMP13 (0.65) | SMN1; SMN2CYP3A4MAPK14MMP13ROCK2 | |
| SCHEMBL29258255 | 0.90 | MMP13 (0.52) | SMN1; SMN2CYP3A4MAPK14MMP13ROCK2 | |
| SCHEMBL29258637 | 0.89 | AKR1C3 (0.54) | SMN1; SMN2CYP3A4MAPK14MMP13ROCK2 | |
| SCHEMBL29258289 | 0.89 | L3MBTL1 (0.63) | SMN1; SMN2CYP3A4MAPK14MMP13ROCK2 | |
| SCHEMBL29258571 | 0.89 | AKR1C3 (0.60) | SMN1; SMN2CYP3A4MAPK14MMP13ROCK2 | |
| SCHEMBL29258251 | 0.88 | HDAC1 (0.47) | MAPK14MMP13ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL28987653 | 0.88 | TSHR (0.64) | SMN1; SMN2TSHRHDAC1HDAC6HDAC3 | |
| SCHEMBL29258544 | 0.88 | NPC1 (0.57) | SMN1; SMN2MAPK14MMP13ROCK2RPS6KA5 | |
| SCHEMBL29258229 | 0.86 | HDAC1 (0.50) | SMN1; SMN2CYP3A4MAPK14MMP13ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |