Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.78 |
| ▸ | NAMPT | P43490 | 16/20 | 0.77 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.74 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.74 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.70 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.70 |
| ▸ | PRKCG | P05129 | 1/20 | 0.70 |
| ▸ | PRKACA | P17612 | 1/20 | 0.70 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | AKT1 | P31749 | 1/20 | 0.70 |
| ▸ | GSK3A | P49840 | 1/20 | 0.70 |
| ▸ | GSK3B | P49841 | 1/20 | 0.70 |
| ▸ | PRKX | P51817 | 1/20 | 0.70 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.70 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.70 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.70 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.70 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379936 | 0.90 | NAMPT (0.80) | NAMPT | |
| SCHEMBL539269 | 0.88 | MMP13 (1.00) | MMP13NAMPTROCK2ROCK1RPS6KA5 | |
| SCHEMBL20379905 | 0.87 | NAMPT (1.00) | NAMPTHTT | |
| SCHEMBL29258723 | 0.86 | NAMPT (0.71) | NAMPT | |
| SCHEMBL4525925 | 0.86 | ROCK2 (1.00) | NAMPTROCK2ROCK1RPS6KA5MAP4K4 | |
| SCHEMBL20379290 | 0.85 | NAMPT (0.88) | NAMPT | |
| SCHEMBL20379933 | 0.85 | NAMPT (0.88) | NAMPT | |
| SCHEMBL20379630 | 0.85 | NAMPT (0.88) | NAMPT | |
| SCHEMBL29258273 | 0.85 | NAMPT (0.70) | NAMPT | |
| SCHEMBL20389217 | 0.84 | NAMPT (1.00) | NAMPTROCK2ROCK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |