Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258255 | 0.90 | MMP13 (0.52) | AKR1C3KDM4ECYP3A4SMN1; SMN2MMP13 | |
| SCHEMBL29258227 | 0.90 | MMP13 (0.65) | AKR1C3AKR1C4CYP3A4SMN1; SMN2MMP13 | |
| SCHEMBL29258321 | 0.89 | AKR1C3 (0.50) | AKR1C3KDM4ECYP3A4MMP13MAPK1 | |
| SCHEMBL29258289 | 0.89 | L3MBTL1 (0.63) | AKR1C3CYP3A4SMN1; SMN2MMP13MAPK14 | |
| SCHEMBL29258637 | 0.89 | AKR1C3 (0.54) | AKR1C3KDM4EAKR1C4CYP3A4SMN1; SMN2 | |
| SCHEMBL29258277 | 0.89 | SMN1; SMN2 (0.57) | AKR1C3CYP3A4SMN1; SMN2MMP13MAPK14 | |
| SCHEMBL29258612 | 0.88 | NPC1 (0.57) | AKR1C3AKR1C4CYP3A4SMN1; SMN2MMP13 | |
| SCHEMBL29258159 | 0.84 | HPGD (0.62) | KDM4EMMP13MAPK14HTTMAPK1 | |
| SCHEMBL29258251 | 0.84 | HDAC1 (0.47) | AKR1C3MMP13MAPK14MAPK1MEN1 | |
| SCHEMBL29258169 | 0.83 | SMN1; SMN2 (0.47) | AKR1C3KDM4ECYP3A4SMN1; SMN2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |