Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22234206 | 0.90 | CYP19A1 (0.68) | CYP19A1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4664487 | 0.83 | LMNA (0.68) | KMT2AMEN1ALDH1A1LMNACA2 | |
| SCHEMBL29258301 | 0.83 | CYP19A1 (0.59) | CYP19A1KMT2AMEN1ALDH1A1CA2 | |
| SCHEMBL29258799 | 0.81 | LMNA (0.60) | KMT2AMEN1LMNACA2CA1 | |
| SCHEMBL27639297 | 0.80 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL121841 | 0.79 | CYP19A1 (0.80) | CYP19A1KMT2AMEN1ALDH1A1CA2 | |
| SCHEMBL20946398 | 0.78 | LMNA (0.57) | CYP19A1KMT2AMEN1LMNACA2 | |
| SCHEMBL4661775 | 0.78 | CA2 (0.76) | CYP19A1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7978856 | 0.77 | KMT2A (0.58) | KMT2AMEN1ALDH1A1LMNACA2 | |
| SCHEMBL2496626 | 0.75 | CYP19A1 (0.74) | CYP19A1KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |