Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423082 | 0.82 | L3MBTL1 (0.51) | KMT2AMEN1CHRM2PTPRFPTPN2 | |
| SCHEMBL1041853 | 0.82 | MEN1 (0.69) | KMT2AMEN1CHRM2PTPRFPTPN2 | |
| SCHEMBL628651 | 0.82 | CHRM2 (0.72) | KMT2AMEN1CHRM2PTPRFPTPN2 | |
| SCHEMBL17294506 | 0.78 | KMT2A (0.61) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL18610468 | 0.77 | PTPRF (0.62) | KMT2AMEN1PTPRFPTPN2PTPN1 | |
| SCHEMBL29258367 | 0.77 | CYP19A1 (0.59) | KMT2AMEN1CA1CA2MAPT | |
| SCHEMBL6071681 | 0.76 | MPO (0.60) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL15417018 | 0.76 | KMT2A (0.50) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL8228985 | 0.76 | THRB (0.51) | KMT2AMEN1CHRM2CA1CA2 | |
| SCHEMBL7246350 | 0.76 | MAOB (0.54) | KMT2AMEN1CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201013-B1 | INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) INHIBITOR; SIDE EFFECT REDUCTION, NON-DRUG RESISTANT | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-13 | — | — | US | disclosed |