Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258393 | 0.99 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1SLC18A3NPC1POLB | |
| SCHEMBL29258565 | 0.98 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1SLC18A3NPC1POLB | |
| SCHEMBL29258417 | 0.90 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1SLC18A3MEN1KMT2A | |
| SCHEMBL29258416 | 0.88 | LRRK2 (0.40) | L3MBTL1ALDH1A1SLC18A3IRAK4KMT2A | |
| SCHEMBL16985296 | 0.81 | IRAK4 (0.41) | L3MBTL1ALDH1A1MAPTACHEIRAK4 | |
| SCHEMBL29258780 | 0.81 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1SMN1; SMN2ACHEIRAK4 | |
| SCHEMBL29258406 | 0.81 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2ACHEMEN1 | |
| SCHEMBL29258517 | 0.81 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1SMN1; SMN2ACHEMEN1 | |
| SCHEMBL29258363 | 0.80 | IRAK4 (0.38) | L3MBTL1ALDH1A1SMN1; SMN2IRAK4KMT2A | |
| SCHEMBL29258806 | 0.79 | SIGMAR1 (0.39) | L3MBTL1ALDH1A1ACHEIRAK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108708-A | Aminopyrimidine derivative with antifungal activity and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |