SCHEMBL29259671

SCHEMBL29259671

CC(=O)NC1=C(Cl)C(=O)C2=CCCC=C2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 7/20 0.54
HSP90AB1 P08238 7/20 0.54
S100A4 P26447 2/20 0.46
ATM Q13315 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CCR6 P51684 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
PKM P14618 1/20 0.41
MAPK1 P28482 1/20 0.41
MCL1 Q07820 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
HKDC1 Q2TB90 2/20 0.38
MEN1 O00255 1/20 0.38
PABPC1 P11940 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9701136 0.79 HSP90AA1 (0.66) HSP90AA1HSP90AB1S100A4ATMALDH1A1
SCHEMBL29259664 0.77 HSP90AA1 (0.37) HSP90AA1HSP90AB1S100A4ATMALDH1A1
SCHEMBL12653075 0.72 CES2 (0.44) HSP90AA1ALDH1A1MAPTNPSR1HTT
SCHEMBL31087717 0.70 HSP90AA1 (1.00) HSP90AA1HSP90AB1S100A4ATMALDH1A1
SCHEMBL6190569 0.70 HSP90AA1 (1.00) HSP90AA1HSP90AB1S100A4ATMALDH1A1
SCHEMBL14593445 0.69 HSP90AA1 (0.68) HSP90AA1HSP90AB1S100A4ATMALDH1A1
SCHEMBL12247191 0.64 HSP90AA1 (0.38) HSP90AA1HSP90AB1S100A4ALDH1A1HTT
SCHEMBL5960697 0.61 SMN1; SMN2 (0.34) ALDH1A1MAPTHTTRAB9AL3MBTL1
SCHEMBL12247202 0.58 ALDH1A1 (0.35) HSP90AA1HSP90AB1ALDH1A1MAPTHTT
SCHEMBL16372323 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768801-B Condensed quinone oxime imidazoles and their onium derivatives, their preparation and use 上海交通大学 2026-05-19 CN disclosed
CN-116768801-A Condensed quinone oxime imidazoles and their onium derivatives, their preparation and use 上海交通大学 2023-09-19 CN disclosed