SCHEMBL29259797

SCHEMBL29259797

COc1ccc(C(C)NS(=O)(=O)c2ccc(OC)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.68
CA2 P00918 3/20 0.68
ACHE P22303 1/20 0.68
CNR1 P21554 6/20 0.67
MMP2 P08253 7/20 0.62
CA12 O43570 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CNR2 P34972 5/20 0.58
DRD4 P21917 1/20 0.58
DRD3 P35462 1/20 0.58
HTR6 P50406 1/20 0.58
MMP9 P14780 5/20 0.56
MMP8 P22894 5/20 0.56
MMP13 P45452 4/20 0.56
MMP1 P03956 3/20 0.56
MMP3 P08254 2/20 0.55
MMP7 P09237 2/20 0.55
MMP14 P50281 1/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28354122 0.94 CNR1 (0.77) CA1CA2ACHECNR1MMP2
SCHEMBL29259802 0.92 CNR1 (0.60) CA1CA2ACHECNR1MMP2
SCHEMBL25181527 0.92 CA1 (0.63) CA1CA2ACHECNR1MMP2
SCHEMBL25264635 0.92 CNR1 (0.60) CA1CA2ACHECNR1MMP2
SCHEMBL29259795 0.92 CNR1 (0.60) CA1CA2ACHECNR1MMP2
SCHEMBL25181528 0.92 CA1 (0.63) CA1CA2ACHECNR1MMP2
SCHEMBL25193424 0.92 CNR1 (0.60) CA1CA2ACHECNR1MMP2
SCHEMBL29259799 0.92 CNR1 (0.60) CA1CA2ACHECNR1MMP2
SCHEMBL11065834 0.92 CNR1 (0.70) CA1CA2ACHECNR1MMP2
SCHEMBL29260162 0.90 CNR1 (0.61) CA1CA2ACHECNR1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924125-A Method for preparing sulfonamide derivative through visible light catalysis without metal participation 苏州大学 2024-04-26 CN disclosed