SCHEMBL29259795

SCHEMBL29259795

COc1ccc(C(C)NS(=O)(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.60
CNR2 P34972 6/20 0.60
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
ACHE P22303 1/20 0.59
CA12 O43570 2/20 0.55
MMP2 P08253 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
S1PR1 P21453 1/20 0.53
DRD4 P21917 1/20 0.52
DRD3 P35462 1/20 0.52
HTR6 P50406 1/20 0.52
ALDH1A1 P00352 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
EGFR P00533 1/20 0.51
ERBB2 P04626 1/20 0.51
FFAR4 Q5NUL3 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29259797 0.92 CA1 (0.68) CNR1CNR2CA1CA2ACHE
SCHEMBL28354122 0.87 CNR1 (0.77) CNR1CNR2CA1CA2ACHE
SCHEMBL25181527 0.85 CA1 (0.63) CNR1CNR2CA1CA2ACHE
SCHEMBL25264635 0.85 CNR1 (0.60) CNR1CNR2CA1CA2ACHE
SCHEMBL25193424 0.85 CNR1 (0.60) CNR1CNR2CA1CA2ACHE
SCHEMBL25181528 0.85 CA1 (0.63) CNR1CNR2CA1CA2ACHE
SCHEMBL29259799 0.85 CNR1 (0.60) CNR1CNR2CA1CA2ACHE
SCHEMBL29259802 0.85 CNR1 (0.60) CNR1CNR2CA1CA2ACHE
SCHEMBL11065834 0.85 CNR1 (0.70) CNR1CNR2CA1CA2ACHE
SCHEMBL29260041 0.83 PGR (0.64) CNR1CNR2CA1CA2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924125-A Method for preparing sulfonamide derivative through visible light catalysis without metal participation 苏州大学 2024-04-26 CN disclosed