SCHEMBL11065834

SCHEMBL11065834

COc1ccc(S(=O)(=O)NC(C)c2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.70
ALDH1A1 P00352 5/20 0.64
POLB P06746 2/20 0.60
KDM4E B2RXH2 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2D6 P10635 1/20 0.60
CYP2C19 P33261 1/20 0.60
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
ACHE P22303 1/20 0.58
MMP2 P08253 2/20 0.57
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
LOXL2 Q9Y4K0 3/20 0.56
AOC3 Q16853 2/20 0.56
MMP9 P14780 2/20 0.55
MMP1 P03956 1/20 0.55
MMP3 P08254 1/20 0.55
MMP7 P09237 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29259797 0.92 CA1 (0.68) CNR1ALDH1A1POLBCA1CA2
SCHEMBL28354122 0.86 CNR1 (0.77) CNR1ALDH1A1CA1CA2ACHE
SCHEMBL25193424 0.85 CNR1 (0.60) CNR1CA1CA2ACHEMMP2
SCHEMBL25264635 0.85 CNR1 (0.60) CNR1CA1CA2ACHEMMP2
SCHEMBL29259795 0.85 CNR1 (0.60) CNR1ALDH1A1CA1CA2ACHE
SCHEMBL25181527 0.85 CA1 (0.63) CNR1CA1CA2ACHEMMP2
SCHEMBL25181528 0.85 CA1 (0.63) CNR1CA1CA2ACHEMMP2
SCHEMBL29259802 0.85 CNR1 (0.60) CNR1ALDH1A1CA1CA2ACHE
SCHEMBL29259799 0.85 CNR1 (0.60) CNR1ALDH1A1POLBCA1CA2
SCHEMBL28426090 0.85 ALDH1A1 (0.73) CNR1ALDH1A1POLBCYP2C19CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024164666-A1 METHOD FOR PREPARING BENZYLAMINE DERIVATIVE BY VISIBLE LIGHT-PROMOTED NICKEL-CATALYZED AMINATION OF BENZYL C-H BONDS 上海沃凯生物技术有限公司 2024-08-15 WO disclosed
CN-116063209-B Method for preparing benzylamine derivative by catalyzing amination of benzyl C-H bond through nickel under promotion of visible light 上海沃凯生物技术有限公司 2024-04-09 CN disclosed
CN-116063209-A Method for preparing benzylamine derivative by catalyzing amination of benzyl C-H bond through nickel under promotion of visible light 上海沃凯生物技术有限公司 2023-05-05 CN disclosed
US-4468245-A N-(2,3-Epoxypropylene)-n-aralkylsulfonamide and herbicidal compositions containing the same MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-08-28 US disclosed