Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 7/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | MMP8 | P22894 | 5/20 | 0.53 |
| ▸ | MMP13 | P45452 | 4/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | MMP7 | P09237 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 5/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25193424 | 1.00 | CNR1 (0.60) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL29259797 | 0.92 | CA1 (0.68) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL28354122 | 0.87 | CNR1 (0.77) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL29259802 | 0.85 | CNR1 (0.60) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL25181527 | 0.85 | CA1 (0.63) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL29259799 | 0.85 | CNR1 (0.60) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL25181528 | 0.85 | CA1 (0.63) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL29259795 | 0.85 | CNR1 (0.60) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL11065834 | 0.85 | CNR1 (0.70) | CNR1CA1CA2ACHEMMP2 | |
| SCHEMBL29260162 | 0.83 | CNR1 (0.61) | CNR1CA1CA2ACHEMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240382474-A1 | ENPP1 MODULATORS AND USES THEREOF | VIR BIOTECHNOLOGY INC (US) | 2024-11-21 | — | — | US | disclosed |
| EP-4433455-A1 | ENPP1 MODULATORS AND USES THEREOF | VIR Biotechnology, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023225001-A1 | NAPHTHYRIDINE BASED ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023086638-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382474-A1 | ENPP1 MODULATORS AND USES THEREOF | ENPP1, ENPP2, ENPP3 | CNR1 2268/4885CA1 4856/4885CA2 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.