Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807002 | 0.88 | MEN1 (0.34) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL26695691 | 0.82 | LMNA (0.40) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL97166 | 0.80 | MEN1 (0.41) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL28079344 | 0.79 | HPGD (0.39) | MEN1KMT2ATDP1HTTATM | |
| SCHEMBL5934008 | 0.79 | LMNA (0.46) | MEN1KMT2ATDP1LMNAALDH1A1 | |
| SCHEMBL28757976 | 0.78 | CES2 (0.46) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL27966648 | 0.78 | PTPN2 (0.40) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL28192380 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL27792680 | 0.78 | NPC1 (0.51) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL4230070 | 0.76 | MAPT (0.49) | KMT2ATDP1HTTATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290327-A | Preparation method of rasidipine Chinese pharmacopoeia impurity 3 | 上海奥博生物医药股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290326-A | Preparation method of rasidipine Chinese pharmacopoeia impurity 1 | 上海奥博生物医药股份有限公司 | 2024-07-05 | — | — | CN | disclosed |