Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 8/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | WNT3 | P56703 | 1/20 | 0.33 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942515 | 0.84 | TRPV1 (0.41) | RORCHTR2AHTR2CTRPV1LRRK2 | |
| SCHEMBL30833471 | 0.78 | RORC (0.36) | RORCTRPV1LRRK2WNT3SFRP1 | |
| SCHEMBL30833492 | 0.77 | RORC (0.36) | RORCTRPV1TRPM8LRRK2WNT3 | |
| SCHEMBL30833449 | 0.76 | RORC (0.42) | RORCWNT3SFRP1 | |
| SCHEMBL30833394 | 0.75 | RORC (0.35) | RORCTRPV1LRRK2WNT3SFRP1 | |
| SCHEMBL30833437 | 0.75 | RORC (0.37) | RORCTRPV1SCN10AWNT3SFRP1 | |
| SCHEMBL30833421 | 0.74 | RORC (0.36) | RORCSCN10ALRRK2WNT3SFRP1 | |
| SCHEMBL17948885 | 0.72 | TRPV1 (0.47) | RORCTRPV1 | |
| SCHEMBL17949343 | 0.72 | CA12 (0.39) | TRPV1 | |
| SCHEMBL29529392 | 0.72 | CA12 (0.39) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |