Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | WNT3 | P56703 | 1/20 | 0.33 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942488 | 0.84 | SPR (0.37) | RORCEPHX2PKLRKMT2ALMNA | |
| SCHEMBL30833471 | 0.83 | RORC (0.36) | RORCEPHX2WNT3SFRP1KMT2A | |
| SCHEMBL30833492 | 0.82 | RORC (0.36) | RORCEPHX2WNT3SFRP1KMT2A | |
| SCHEMBL30833512 | 0.79 | WNT3 (0.36) | WNT3SFRP1PKLRKMT2ANAMPT | |
| SCHEMBL30833449 | 0.78 | RORC (0.42) | RORCEPHX2WNT3SFRP1KMT2A | |
| SCHEMBL29262256 | 0.75 | RORC (0.38) | RORCWNT3SFRP1TRPV1LRRK2 | |
| SCHEMBL30833437 | 0.75 | RORC (0.37) | RORCEPHX2WNT3SFRP1LMNA | |
| SCHEMBL30833421 | 0.73 | RORC (0.36) | RORCEPHX2WNT3SFRP1LMNA | |
| SCHEMBL30833383 | 0.73 | MEN1 (0.42) | RORCEPHX2WNT3SFRP1KMT2A | |
| SCHEMBL30833430 | 0.72 | LMNA (0.39) | RORCEPHX2WNT3SFRP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |