SCHEMBL29264141

SCHEMBL29264141

O=C(O)N1CCC[C@H]2CNCC21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CHRNB2 P17787 6/20 0.35
CHRNB4 P30926 6/20 0.35
CHRNA3 P32297 6/20 0.35
CHRNA4 P43681 6/20 0.35
CHRNA7 P36544 4/20 0.35
DPP4 P27487 4/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
POLB P06746 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
FAP Q12884 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
PARP1 P09874 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL652903 1.00 NPC1 (0.36) NPC1RAB9ASMN1; SMN2CHRNB2CHRNB4
SCHEMBL652904 1.00 NPC1 (0.36) NPC1RAB9ASMN1; SMN2CHRNB2CHRNB4
SCHEMBL652905 1.00 NPC1 (0.36) NPC1RAB9ASMN1; SMN2CHRNB2CHRNB4
SCHEMBL3579211 0.89 PARP1 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7
SCHEMBL3582591 0.89 PARP1 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7
SCHEMBL1033901 0.89 PARP1 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7
SCHEMBL2484748 0.84 SLC6A1 (0.42) NPC1RAB9ASMN1; SMN2DPP4HTR2C
SCHEMBL1982802 0.84 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7
SCHEMBL1982803 0.84 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7
SCHEMBL1982800 0.84 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118147101-A Method for preparing moxifloxacin intermediate by enzyme catalysis 湖州颐盛生物科技有限公司 2024-06-07 CN disclosed