Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CPN1 | P15169 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652905 | 0.84 | NPC1 (0.36) | SMN1; SMN2NPC1RAB9AHTR2CDPP4 | |
| SCHEMBL652903 | 0.84 | NPC1 (0.36) | SMN1; SMN2NPC1RAB9AHTR2CDPP4 | |
| SCHEMBL652904 | 0.84 | NPC1 (0.36) | SMN1; SMN2NPC1RAB9AHTR2CDPP4 | |
| SCHEMBL29264141 | 0.84 | NPC1 (0.36) | SMN1; SMN2NPC1RAB9AHTR2CDPP4 | |
| SCHEMBL19974288 | 0.81 | NPC1 (0.43) | SMN1; SMN2TSHRNPC1RAB9ADPP4 | |
| SCHEMBL15533257 | 0.81 | NPC1 (0.43) | SMN1; SMN2TSHRNPC1RAB9ADPP4 | |
| SCHEMBL20744258 | 0.81 | SLC6A1 (0.36) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL334462 | 0.81 | SLC6A1 (0.36) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL18692612 | 0.81 | SLC6A1 (0.36) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL3169796 | 0.80 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9ADPP7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117254-A1 | PIPERIDINE AMIDES AS MODULATORS OF THE GHRELIN RECEPTOR | PROSIDION LIMITED (GB) | 2011-09-29 | — | — | WO | disclosed |