SCHEMBL29264238

SCHEMBL29264238

CNCc1ccc(-c2ccccc2F)c(-c2cc(Cl)ccc2S(N)(=O)=O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HTR7 P34969 2/20 0.38
HTR1A P08908 1/20 0.38
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR1E P28566 1/20 0.38
HTR2B P41595 1/20 0.38
HTR5A P47898 1/20 0.38
HTR6 P50406 1/20 0.38
F10 P00742 1/20 0.38
PTGES2 Q9H7Z7 6/20 0.37
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29264163 0.89 NPC1 (0.42) LMNAMAPTSMN1; SMN2HTR7HTR1A
SCHEMBL29264203 0.89 HTR7 (0.40) HTR7HTR1AHTR1DHTR1BHTR2A
SCHEMBL29264181 0.88 HTR7 (0.37) HTR7HTR1AHTR1DHTR1BHTR2A
SCHEMBL29264251 0.87 F10 (0.37) LMNAHTR7HTR1AHTR1DHTR1B
SCHEMBL29264180 0.85 ALOX5AP (0.39) HTR7PTGES2ALOX5APFEN1
SCHEMBL29264230 0.85 HTR7 (0.42) LMNAMAPTSMN1; SMN2HTR7HTR1A
SCHEMBL29264167 0.83 HTR7 (0.36) LMNAHTR7HTR1AHTR1DHTR1B
SCHEMBL29264185 0.83 HTR7 (0.46) HTR7HTR1AHTR1DHTR1BHTR2A
SCHEMBL29264207 0.82 HTR7 (0.38) HTR7HTR1AHTR1DHTR1BHTR2A
SCHEMBL29264201 0.81 HTR7 (0.38) LMNAHTR7HTR1AHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206476-A Alkylamine substituted sulfonamide compound and application thereof 上海璃道医药科技有限公司 2024-06-18 CN disclosed