SCHEMBL29264181

SCHEMBL29264181

CNCc1ccc(-c2ccccc2F)c(-c2cc(C)ccc2S(N)(=O)=O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.37
ALOX5AP P20292 5/20 0.36
FEN1 P39748 5/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
CA12 O43570 1/20 0.35
ELANE P08246 1/20 0.35
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
HTR1A P08908 1/20 0.34
HTR1D P28221 1/20 0.34
HTR1B P28222 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR1E P28566 1/20 0.34
HTR2B P41595 1/20 0.34
HTR5A P47898 1/20 0.34
HTR6 P50406 1/20 0.34
CA4 P22748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29264163 0.90 NPC1 (0.42) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264203 0.90 HTR7 (0.40) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264238 0.88 LMNA (0.38) HTR7ALOX5APFEN1HTR1AHTR1D
SCHEMBL29264251 0.88 F10 (0.37) HTR7ALOX5APFEN1HTR1AHTR1D
SCHEMBL29264230 0.86 HTR7 (0.42) HTR7CA1CA2CA9CA12
SCHEMBL29264180 0.86 ALOX5AP (0.39) HTR7ALOX5APFEN1PTGES2SCN9A
SCHEMBL29264207 0.85 HTR7 (0.38) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264168 0.82 HTR7 (0.39) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264167 0.82 HTR7 (0.36) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264201 0.80 HTR7 (0.38) HTR7CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206476-A Alkylamine substituted sulfonamide compound and application thereof 上海璃道医药科技有限公司 2024-06-18 CN disclosed