SCHEMBL29264203

SCHEMBL29264203

CNCc1ccc(-c2ccccc2F)c(-c2ccccc2S(N)(=O)=O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.40
ALOX5AP P20292 6/20 0.39
FEN1 P39748 6/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
HTR1A P08908 1/20 0.37
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR1E P28566 1/20 0.37
HTR2B P41595 1/20 0.37
HTR5A P47898 1/20 0.37
HTR6 P50406 1/20 0.37
CA9 Q16790 1/20 0.36
PTGES2 Q9H7Z7 2/20 0.36
SCN9A Q15858 2/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29264163 0.91 NPC1 (0.42) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264207 0.91 HTR7 (0.38) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264181 0.90 HTR7 (0.37) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264238 0.89 LMNA (0.38) HTR7ALOX5APFEN1HTR1AHTR1D
SCHEMBL29264251 0.89 F10 (0.37) HTR7ALOX5APFEN1HTR1AHTR1D
SCHEMBL29264168 0.87 HTR7 (0.39) HTR7ALOX5APFEN1CA1CA2
SCHEMBL29264230 0.87 HTR7 (0.42) HTR7CA1CA2HTR1AHTR1D
SCHEMBL29264249 0.86 HTR7 (0.47) HTR7CA1CA2HTR1AHTR1D
SCHEMBL29264198 0.86 CA2 (0.42) HTR7CA1CA2HTR1AHTR1D
SCHEMBL29264247 0.85 HTR7 (0.48) HTR7CA1CA2HTR1AHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206476-A Alkylamine substituted sulfonamide compound and application thereof 上海璃道医药科技有限公司 2024-06-18 CN disclosed