Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19701769 | 0.86 | NLRP3 (0.46) | RAB9AKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL29264301 | 0.85 | NQO2 (0.42) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL29991677 | 0.80 | ATR (0.47) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL28829529 | 0.80 | CYP3A4 (0.41) | MTNR1BMTNR1AKMT2AMEN1GAA | |
| SCHEMBL729159 | 0.77 | ATR (0.42) | MTNR1BMTNR1AGAAALDH1A1 | |
| SCHEMBL14670856 | 0.76 | HPGD (0.70) | HPGDNPC1RAB9AKMT2AHTT | |
| SCHEMBL3417084 | 0.75 | HPGD (0.60) | HPGDNPC1RAB9AKMT2AHTT | |
| SCHEMBL27484947 | 0.75 | ALDH1A1 (0.44) | HPGDKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL20514222 | 0.75 | PKM (0.50) | — | |
| SCHEMBL10437433 | 0.74 | NLRP3 (0.56) | HTTNPSR1CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271200-A | Industrial preparation method and application of lacosamide | 北京澳合药物研究院有限公司 | 2024-07-02 | — | — | CN | disclosed |