Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952388 | 0.88 | DDB1 (0.50) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL30643667 | 0.87 | DDB1 (0.49) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL25824549 | 0.86 | DDB1 (0.48) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL31630927 | 0.85 | DDB1 (0.49) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL25034753 | 0.84 | DDB1 (0.48) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL31630916 | 0.84 | DDB1 (0.48) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL22119507 | 0.84 | DDB1 (0.59) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL29265203 | 0.82 | CRBN (0.55) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL30525413 | 0.82 | CRBN (0.55) | DDB1CRBNMAPTLMNAALDH1A1 | |
| SCHEMBL30703627 | 0.82 | DDB1 (0.48) | DDB1CRBNMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271284-A | Estrogen receptor modulators and uses thereof | 江苏威凯尔医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |