Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952388 | 0.89 | DDB1 (0.50) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25824549 | 0.87 | DDB1 (0.48) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29264332 | 0.87 | DDB1 (0.51) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31630927 | 0.86 | DDB1 (0.49) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25034753 | 0.85 | DDB1 (0.48) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31630916 | 0.85 | DDB1 (0.48) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22119507 | 0.85 | DDB1 (0.59) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL26641240 | 0.84 | DDB1 (0.43) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29265203 | 0.83 | CRBN (0.55) | DDB1CRBNMAPTALDH1A1LMNA | |
| SCHEMBL30525413 | 0.83 | CRBN (0.55) | DDB1CRBNMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |