Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264847 | 0.87 | KDM4E (0.50) | TSHRKMT2ANOTUMSMN1; SMN2KDM4E | |
| SCHEMBL29264859 | 0.85 | NOTUM (0.58) | TSHRNOTUMSMN1; SMN2KDM4ES1PR2 | |
| SCHEMBL30612320 | 0.81 | KMT2A (0.52) | TSHRKMT2ANOTUMSMN1; SMN2NSD2 | |
| SCHEMBL29264863 | 0.79 | SLC6A4 (0.45) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL29264882 | 0.78 | KDM4E (0.47) | TSHRKMT2ANOTUMSMN1; SMN2KDM4E | |
| SCHEMBL29264868 | 0.78 | MAPK8 (0.50) | TSHRKMT2ANOTUMSMN1; SMN2KDM4E | |
| SCHEMBL29264884 | 0.76 | MAPK8 (0.50) | TSHRKMT2ANOTUMSMN1; SMN2KDM4E | |
| SCHEMBL29264864 | 0.76 | NPSR1 (0.47) | TSHRKMT2ANOTUMSMN1; SMN2KDM4E | |
| SCHEMBL29264866 | 0.76 | SLC6A3 (0.51) | KMT2ASMN1; SMN2KDM4ETDP2NSD2 | |
| SCHEMBL14120692 | 0.76 | PPARG (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |