Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23141132 | 0.85 | TRPV4 (1.00) | TRPV4CNR2 | |
| SCHEMBL29420276 | 0.85 | TRPV4 (1.00) | TRPV4CNR2 | |
| SCHEMBL15114555 | 0.85 | TRPV4 (0.53) | TRPV4PGRALDH1A1TYRTSHR | |
| SCHEMBL3532245 | 0.83 | TRPV4 (0.51) | TRPV4ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL2925204 | 0.79 | TRPV4 (0.51) | TRPV4PGRALDH1A1TYRTSHR | |
| SCHEMBL2920395 | 0.79 | TRPV4 (0.47) | TRPV4PGRALDH1A1TYRLMNA | |
| SCHEMBL16259892 | 0.79 | TRPV4 (0.47) | TRPV4PGRALDH1A1TSHRLMNA | |
| SCHEMBL16259574 | 0.78 | TRPV4 (0.46) | TRPV4PGRALDH1A1TSHRLMNA | |
| SCHEMBL1929488 | 0.77 | TRPV4 (0.44) | TRPV4PGRALDH1A1TYRTSHR | |
| SCHEMBL18894564 | 0.77 | LMNA (0.48) | TRPV4ALDH1A1TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226312-A1 | METHOD FOR PRODUCING 3-MERCAPTOANILINE COMPOUND | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-09-08 | — | — | EP | disclosed |