Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11951611 | 0.82 | SLC9A1 (0.50) | FABP3FABP4FABP5ALDH1A1SMN1; SMN2 | |
| SCHEMBL25754886 | 0.81 | LMNA (0.47) | TRPV4ALDH1A1SLC9A1SLC9A2LMNA | |
| SCHEMBL18894564 | 0.81 | LMNA (0.48) | TRPV4ALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL11400623 | 0.81 | FABP3 (0.53) | FABP3FABP4FABP5ALDH1A1SMN1; SMN2 | |
| SCHEMBL17093011 | 0.81 | ALDH1A1 (0.41) | FABP3FABP4FABP5ALDH1A1SMN1; SMN2 | |
| SCHEMBL29469912 | 0.81 | ALDH1A1 (0.41) | FABP3FABP4FABP5ALDH1A1SMN1; SMN2 | |
| SCHEMBL25759570 | 0.79 | L3MBTL1 (0.39) | TRPV4ALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL4636860 | 0.78 | CNR2 (0.43) | TRPV4ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL2926545 | 0.77 | TRPV4 (0.73) | TRPV4ALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL11326388 | 0.77 | FABP3 (0.41) | FABP3FABP4FABP5ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210834-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2023-07-06 | — | — | US | disclosed |
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |
| US-7956193-B2 | Intramolecular C-H amination with sulfonyl azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-06-07 | — | — | US | disclosed |
| US-7956193-B2 | Intramolecular C-H amination with sulfonyl azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-06-07 | — | — | US | disclosed |
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | NATIONAL SCIENCE FOUNDATION | 2010-03-11 | — | — | US | disclosed |
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | NATIONAL SCIENCE FOUNDATION | 2010-03-11 | — | — | US | disclosed |
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | NATIONAL SCIENCE FOUNDATION | 2010-03-11 | — | — | US | disclosed |
| EP-1265858-B1 | HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS | DU PONT (US) | 2004-05-19 | — | — | EP | disclosed |
| US-6667421-B2 | Hydrogenating an aryl sulfonyl chloride with hydrogen in a solvent in the presence of a palladium catalyst and a base whose conjugate acid pka is >/=2 | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-23 | — | — | US | disclosed |
| US-20030055290-A1 | Hydrogen reduction of sulfonyl chlorides to thiols | THE TEXAS A&M UNIVERSITY SYSTEM | 2003-03-20 | — | — | US | disclosed |
| EP-1265858-A1 | HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001066517-A1 | HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-13 | — | — | WO | disclosed |
| US-3997603-A | Herbicidal halo-di-alkyl benzenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210834-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | EMG1, TRDMT1, BCDIN3D | TRPV4 4398/4885FABP3 3629/4885FABP4 3753/4885 |
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | TST, TIMM9, PPOX | TRPV4 2464/4885FABP3 3466/4885FABP4 3834/4885 |
| US-20030055290-A1 | Hydrogen reduction of sulfonyl chlorides to thiols | TST, IAPP, CBS | TRPV4 3909/4885FABP3 2928/4885FABP4 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.