Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967371 | 0.85 | IDO1 (0.42) | IDO1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL17093165 | 0.82 | LMNA (0.45) | IDO1LMNAKMT2ANOTUMBAZ2B | |
| SCHEMBL30357457 | 0.81 | NPC1 (0.40) | IDO1LMNAKMT2ANOTUMBAZ2B | |
| SCHEMBL29267302 | 0.79 | KDM4E (0.35) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL17093201 | 0.79 | IDO1 (0.44) | IDO1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL31258781 | 0.78 | WDR5 (0.41) | LMNAKMT2ANOTUMBAZ2BBAZ2A | |
| SCHEMBL29267250 | 0.77 | KDM4E (0.38) | LMNAKMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL17093206 | 0.77 | TGFBR1 (0.41) | IDO1LMNANPC1RAB9AGABRA2 | |
| SCHEMBL29277603 | 0.77 | IDO1 (0.40) | IDO1LMNANPC1RAB9AGABRA2 | |
| SCHEMBL27389813 | 0.77 | WDR5 (0.41) | LMNAKMT2ANOTUMBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026104998-A1 | SUBSTITUTED IMIDAZOPYRIDINE COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE | AVELOS THERAPEUTICS INC. (KR) | 2026-05-21 | — | — | WO | disclosed |
| EP-4716532-A2 | BICYCLIC HETEROARYL COMPOUNDS | Quantx Biosciences US, Inc. (US) | 2026-04-01 | — | — | EP | disclosed |
| EP-4688159-A1 | PARG INHIBITORY COMPOUNDS | FoRx Therapeutics AG (CH) | 2026-02-11 | — | — | EP | disclosed |
| US-20240425498-A1 | PARG INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2024-12-26 | — | — | US | disclosed |
| WO-2024243304-A2 | BICYCLIC HETEROARYL COMPOUNDS | QUANTX BIOSCIENCES US, INC. (US) | 2024-11-28 | — | — | WO | disclosed |
| WO-2024209035-A1 | PARG INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2024-10-10 | — | — | WO | disclosed |
| EP-4413001-A1 | PARG INHIBITORY COMPOUNDS | FoRx Therapeutics AG (CH) | 2024-08-14 | — | — | EP | disclosed |
| CN-118055934-A | PARG inhibitory compounds | 福克斯治疗股份公司 | 2024-05-17 | — | — | CN | disclosed |
| WO-2023057389-A1 | PARG INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2023-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425498-A1 | PARG INHIBITORY COMPOUNDS | PARG, PLG, PPIG | IDO1 182/4885LMNA 594/4885KMT2A 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.