Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833660 | 0.80 | GRM5 (0.41) | KMO | |
| SCHEMBL17979362 | 0.74 | TRPA1 (0.34) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL4876024 | 0.73 | LDHA (0.47) | LDHAMEN1ALDH1A1KMT2ACNR1 | |
| SCHEMBL31748742 | 0.73 | HPGD (0.44) | LDHANPC1MEN1ALDH1A1HPGD | |
| SCHEMBL19434146 | 0.73 | LDHA (0.53) | LDHANPC1MEN1ALDH1A1HPGD | |
| SCHEMBL8549213 | 0.72 | JAK2 (0.40) | NPC1MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL899188 | 0.71 | TDP1 (0.45) | NPC1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29411195 | 0.71 | TDP1 (0.45) | NPC1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30996251 | 0.71 | ALOX5AP (0.36) | LDHANPC1MEN1ALDH1A1HPGD | |
| SCHEMBL400693 | 0.71 | ALDH1A1 (0.41) | NPC1MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |