Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 2/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682127 | 0.72 | CA12 (0.43) | CA12CA1CA9CNR2LMNA | |
| SCHEMBL655194 | 0.71 | POLB (0.48) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL25319641 | 0.69 | CA12 (0.39) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL30536010 | 0.69 | CA12 (0.39) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL653538 | 0.67 | CISD2 (0.41) | CA12CA1CA9BRD9 | |
| SCHEMBL652964 | 0.67 | CISD2 (0.41) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL12072957 | 0.67 | LCK (0.41) | CA12CA1CA9BRD9CYP1A2 | |
| SCHEMBL28797272 | 0.67 | CYP17A1 (0.43) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL4568018 | 0.67 | NLRP3 (0.55) | LMNANPSR1CYP1A2POLBCYP3A4 | |
| SCHEMBL8297312 | 0.67 | SMN1; SMN2 (0.63) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-B | Substituted tricyclic compounds | 鲁宾有限公司 | 2024-05-24 | — | — | CN | disclosed |