Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310934 | 0.86 | RAB9A (0.47) | RAB9AGAACHRM1CHRM2NOS3 | |
| SCHEMBL23041797 | 0.83 | GAA (0.62) | GAACHRM1NOS3NOS2ALDH1A1 | |
| SCHEMBL6238126 | 0.82 | RAB9A (0.48) | RAB9AGAAALDH1A1HSD11B1JAK2 | |
| SCHEMBL5275189 | 0.82 | RAB9A (0.43) | RAB9AGAACHRM1CHRM2NOS3 | |
| SCHEMBL704010 | 0.82 | RAB9A (0.51) | RAB9AGAACHRM1CHRM2NOS3 | |
| SCHEMBL5676009 | 0.81 | RAB9A (0.55) | RAB9AGAACHRM1CHRM2NOS3 | |
| SCHEMBL794087 | 0.80 | RAB9A (0.50) | RAB9AGAACHRM1CHRM2NOS3 | |
| SCHEMBL8262844 | 0.80 | RAB9A (0.50) | RAB9AGAACHRM1CHRM2NOS3 | |
| SCHEMBL4274531 | 0.79 | GAA (0.49) | RAB9AGAACHRM1CHRM2NOS3 | |
| SCHEMBL793658 | 0.79 | RAB9A (0.49) | RAB9AGAACHRM1CHRM2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940577-A | Tricyclic pyridines as cyclin dependent kinase 7 (CDK 7) inhibitors | 詹森药业有限公司 | 2023-10-24 | — | — | CN | disclosed |