SCHEMBL23041797

SCHEMBL23041797

C#CC1CCN(C(=O)OCC)CC1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.62
ALDH1A1 P00352 4/20 0.54
L3MBTL1 Q9Y468 3/20 0.53
THRB P10828 1/20 0.53
ATM Q13315 1/20 0.53
CHRM1 P11229 1/20 0.53
NOS3 P29474 1/20 0.50
NOS2 P35228 1/20 0.50
MAPT P10636 4/20 0.49
PKM P14618 1/20 0.49
TSHR P16473 2/20 0.49
HTT P42858 2/20 0.48
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
RECQL P46063 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30473383 0.85 LMNA (0.55) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL4631015 0.84 GAA (0.59) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL5035936 0.84 GAA (0.59) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL29269482 0.83 RAB9A (0.46) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL3629079 0.81 GAA (0.70) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL28118094 0.79 GAA (0.73) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL926726 0.79 GAA (0.58) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL1111736 0.79 GAA (0.67) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL9425764 0.78 GAA (0.53) GAAALDH1A1L3MBTL1THRBATM
SCHEMBL26122530 0.78 ALDH1A1 (0.40) GAAALDH1A1MAPTPKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257056-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2025-08-14 US disclosed
US-12319672-B2 Alpha-D-galactopyranoside derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2025-06-03 US disclosed
EP-4021904-B1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2024-01-03 EP disclosed
US-20220281855-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2022-09-08 US disclosed
EP-4021904-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES Idorsia Pharmaceuticals Ltd (CH) 2022-07-06 EP disclosed
CN-114585619-A alpha-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-06-03 CN disclosed
WO-2021038068-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2021-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250257056-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES LGALS1, LGALS3, LGALS2 GAA 185/4885ALDH1A1 251/4885L3MBTL1 2699/4885
US-20220281855-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES LGALS1, LGALS3, LGALS2 GAA 201/4885ALDH1A1 134/4885L3MBTL1 3016/4885
US-12319672-B2 Alpha-D-galactopyranoside derivatives LGALS1, LGALS3, LGALS2 GAA 201/4885ALDH1A1 134/4885L3MBTL1 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.