Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923417 | 1.00 | CTSK (0.45) | CTSKCTSSATMMEN1KMT2A | |
| SCHEMBL2923426 | 0.91 | CTSK (0.42) | CTSKCTSSATMMEN1KMT2A | |
| SCHEMBL2929227 | 0.91 | CTSK (0.42) | CTSKCTSSATMMEN1KMT2A | |
| SCHEMBL2923386 | 0.79 | CTSK (0.46) | CTSKCTSSATMPPARAPPARG | |
| SCHEMBL3055182 | 0.77 | CTSK (0.46) | CTSKCTSSMEN1KMT2APPARA | |
| SCHEMBL25238924 | 0.76 | CTSS (0.50) | CTSKCTSSATMPPARAPPARG | |
| SCHEMBL27159106 | 0.76 | CTSS (0.50) | CTSKCTSSATMPPARAPPARG | |
| SCHEMBL7423496 | 0.76 | CTSS (0.50) | CTSKCTSSATMPPARAPPARG | |
| SCHEMBL15270465 | 0.76 | CTSS (0.50) | CTSKCTSSATMPPARAPPARG | |
| SCHEMBL25282758 | 0.75 | CTSS (0.49) | CTSKCTSSATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225253-A1 | PHOSPHONIC ACID DERIVATES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009069100-A1 | PHOSPHONIC ACID DERIVATES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-06-04 | — | — | WO | disclosed |