SCHEMBL29272

SCHEMBL29272

c1ccc(Cc2c[nH]nn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
CALM1 P0DP23 1/20 0.44
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40
MAOB P27338 1/20 0.39
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TAAR1 Q96RJ0 3/20 0.37
HRH3 Q9Y5N1 1/20 0.37
CD74 P04233 1/20 0.37
MIF P14174 1/20 0.37
LTA4H P09960 1/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
BCAT2 O15382 1/20 0.36
MAPT P10636 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27499662 1.00 ALDH1A1 (0.46) ALDH1A1CALM1HTR2CHTR2BMAOB
SCHEMBL9508013 0.98 ALDH1A1 (0.44) ALDH1A1CALM1HTR2CHTR2BMAOB
SCHEMBL4441815 0.83 ALDH1A1 (0.40) ALDH1A1MAOBKDM4EMAPTLMNA
SCHEMBL2643655 0.82 KCNH2 (0.50) ALDH1A1MAOBRAB9ASMN1; SMN2TDP1
SCHEMBL28117639 0.80 ESR1 (0.48) TAAR1CD74MIF
SCHEMBL6944017 0.80 CYP3A4 (0.48) ALDH1A1MAOBRAB9ASMN1; SMN2TDP1
SCHEMBL1818072 0.80
SCHEMBL27892139 0.79 HTR2A (0.42) MAOBHRH3
SCHEMBL28026394 0.79 TSHR (0.56) RAB9ASMN1; SMN2L3MBTL1HRH3KDM4E
SCHEMBL28758849 0.78 IDO1 (0.43) MAOBSMN1; SMN2TDP1TAAR1ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591253-B Urea feed additive and preparation method and application thereof 山东博沂饲料科技有限公司 2024-09-24 CN claimed
CN-114651898-B Triazole feed additive for improving immunity as well as preparation method and application thereof 天津溢佳同惠科技集团有限公司 2024-04-05 CN claimed
US-11739071-B2 Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors VALO HEALTH, INC. (US) 2023-08-29 US claimed
EP-3850018-B1 ANTIMICROBIAL CONTACT LENSES KERAMED INC (US) 2023-08-23 EP claimed
CN-115477618-A Synthesis method of benzyl triazole 重庆医科大学 2022-12-16 CN claimed
CN-114651898-A Triazole feed additive for improving immunity and preparation method and application thereof 河南湾流生物科技有限公司 2022-06-24 CN claimed
CN-114591252-A Triazole feed additive and preparation method and application thereof 河南湾流生物科技有限公司 2022-06-07 CN claimed
CN-114591253-A Urea feed additive and preparation method and application thereof 河南湾流生物科技有限公司 2022-06-07 CN claimed
EP-3601506-B1 COMPRESSOR WITH BEARINGS AND DISPENSER FOR ADDITIVES CARRIER CORP (US) 2022-06-01 EP claimed
CN-111087748-B Antistatic ABS resin composition with improved chemical resistance and preparation method thereof 上海普利特复合材料股份有限公司 2022-02-15 CN claimed
EP-0682145-A2 Textile treatment CIBA-GEIGY AG (CH) 1995-11-15 EP claimed
US-5326643-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-07-05 US claimed
US-5269815-A Process for the fluorescent whitening of hydrophobic textile material with disperse fluorescent whitening agents from super-critical carbon dioxide CIBA-GEIGY CORPORATION (US) 1993-12-14 US claimed
US-5244946-A Styrenic copolymer/polyacetal/thermoplastic polyurethane or elastomeric copolyester blend compositions THE DOW CHEMICAL COMPANY (US) 1993-09-14 US claimed
EP-0543779-A1 Process for optical bleaching of hydrophobic textile material with disperse optical brightness in supercritical CO2 CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
EP-0536606-A2 An adhesive layer in multilevel packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1993-04-14 EP claimed
US-5196461-A Molding material THE DOW CHEMICAL COMPANY (US) 1993-03-23 US claimed
EP-0442633-A1 Styrenic copolymer/polyacetal blend compositions THE DOW CHEMICAL COMPANY (US) 1991-08-21 EP claimed
EP-0440442-A1 Polymer blend compositions containing a styrenic copolymer, an acetal polymer and a thermoplastic polyester or polycarbonate resin ingredient THE DOW CHEMICAL COMPANY (US) 1991-08-07 EP claimed
EP-0440441-A1 Styrenic copolymer/polyacetal/thermoplastic polyurethane or elastomeric copolyester blend compositions THE DOW CHEMICAL COMPANY (US) 1991-08-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739071-B2 Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors USP7, UBQLN1, UBA7 ALDH1A1 2483/4885CALM1 2731/4885HTR2C 2571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.