Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273417 | 0.92 | NOTUM (0.36) | NOTUMRORCELANE | |
| SCHEMBL23355443 | 0.86 | KMT2A (0.38) | ALDH1A1KDM4EHPGDHSD17B10RORC | |
| SCHEMBL23355438 | 0.82 | PDE4B (0.35) | ALDH1A1KDM4EHPGDHSD17B10ALB | |
| SCHEMBL23355444 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL23355480 | 0.72 | KMT2A (0.37) | ALDH1A1KDM4EHPGDHSD17B10RORC | |
| SCHEMBL24251609 | 0.72 | KMT2A (0.37) | ALDH1A1KDM4EHPGDHSD17B10RORC | |
| SCHEMBL23355473 | 0.72 | KMT2A (0.36) | ALDH1A1KDM4EHPGDHSD17B10RORC | |
| SCHEMBL29273408 | 0.71 | TTR (0.45) | ALDH1A1RORCTTRPDE4BPDE4D | |
| SCHEMBL24455511 | 0.71 | MAPT (0.42) | ALDH1A1KDM4EHPGDHSD17B10DHODH | |
| SCHEMBL24251412 | 0.70 | MEN1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |