Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273416 | 0.91 | RORC (0.41) | TTRSLC22A12RORCRARG | |
| SCHEMBL23355436 | 0.86 | JAK1 (0.39) | NPC1MAPTRAB9ASMN1; SMN2MAPK14 | |
| SCHEMBL30933433 | 0.78 | MAPK14 (0.43) | TP53MAPTSMN1; SMN2MAPK14RORC | |
| SCHEMBL23355447 | 0.78 | MAPK14 (0.43) | TP53MAPTSMN1; SMN2MAPK14RORC | |
| SCHEMBL29273412 | 0.74 | ALDH1A1 (0.38) | TP53MAPTSMN1; SMN2SLC22A12MEN1 | |
| SCHEMBL29273410 | 0.71 | ALDH1A1 (0.37) | TTRMAPTRORCPDE4BPDE4D | |
| SCHEMBL23355438 | 0.69 | PDE4B (0.35) | TTRMAPTRORCPDE4BPDE4D | |
| SCHEMBL4682390 | 0.69 | TTR (0.46) | TTRRORC | |
| SCHEMBL30205002 | 0.67 | HCAR3 (0.45) | TP53MAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9907615 | 0.65 | HTR5A (0.59) | TTRSMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |