SCHEMBL29273639

SCHEMBL29273639

CCS(=O)(=O)O.Cc1cc(C)c(C)cc1C

nearest known ligand 0.41

Known targets — ChEMBL curated mechanism

FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.38
TSHR P16473 3/20 0.38
LMNA P02545 2/20 0.38
PGK1 P00558 2/20 0.36
PGK2 P07205 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 5/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
HTT P42858 1/20 0.35
FABP4 P15090 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20462946 0.78 PGK1 (0.39) RAPGEF4LMNAPGK1PGK2TDP1
SCHEMBL3796246 0.77
SCHEMBL1904 0.77
SCHEMBL126970 0.77
SCHEMBL2058760 0.77 CA5A (0.46) TSHRLMNATDP1ALDH1A1CYP3A4
Benzene SCHEMBL22443739 0.74 PSIP1 (0.41) TSHRLMNATDP1ALDH1A1SMN1; SMN2
Methyl Alcohol SCHEMBL23421569 0.73
SCHEMBL20583855 0.73
SCHEMBL20533648 0.73
SCHEMBL22581624 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118345467-A Cyanide-free gold plating solution and gold plating method 光华科学技术研究院(广东)有限公司 2024-07-16 CN claimed