Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587696 | 0.86 | ALDH1A1 (0.68) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL40607 | 0.85 | ALDH1A1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9965452 | 0.85 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9769704 | 0.84 | ALDH1A1 (0.55) | SMN1; SMN2LMNAALDH1A1TSHRMAPT | |
| SCHEMBL9076056 | 0.84 | TDP1 (0.53) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7118572 | 0.83 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7191427 | 0.83 | HSD17B10 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL30956245 | 0.83 | HSD17B10 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1246299 | 0.83 | KEAP1 (0.55) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL301933 | 0.81 | ALDH1A1 (0.69) | NPC1RAB9AALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239888-A | Modularized synthesis method and application of acridine compound | 厦门大学 | 2024-06-25 | — | — | CN | disclosed |