Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.36 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.36 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7809563 | 0.91 | PRSS1 (0.44) | PRSS1PTGER4GAAMAPTKDM4E | |
| SCHEMBL6657713 | 0.84 | KMT2A (0.37) | PRSS1MAPTKDM4ETHRBKMT2A | |
| SCHEMBL6573252 | 0.84 | PRSS1 (0.36) | PRSS1MAPTKDM4EALDH1A1HTT | |
| SCHEMBL6571957 | 0.83 | PRSS1 (0.38) | PRSS1KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL24443647 | 0.82 | TSHR (0.41) | PRSS1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL5162037 | 0.82 | ALDH1A1 (0.46) | PRSS1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL6573315 | 0.82 | KMT2A (0.37) | PRSS1ALDH1A1KMT2AFCGR3BFCGR1A | |
| SCHEMBL6571430 | 0.82 | PRSS1 (0.37) | PRSS1ALDH1A1KMT2AFCGR3BFCGR1A | |
| SCHEMBL10608893 | 0.82 | PRSS1 (0.50) | PRSS1PTGER4GAAMAPTALDH1A1 | |
| SCHEMBL5017658 | 0.81 | HDAC1 (0.47) | PRSS1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1733715-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and a heterocyclic direct dye | OREAL (FR) | 2010-01-27 | — | — | EP | claimed |
| WO-2015086675-A1 | PROCESS FOR DYEING KERATIN FIBRES USING COLOURED OLIGOMERS AND/OR POLYMERS DERIVED FROM SELF-OXIDIZING COMPOUNDS, COMPOSITION AND COLOURING AGENT FOR THE SAME | L'OREAL (FR) | 2015-06-18 | — | — | WO | disclosed |
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |