Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	PRSS1	P07477	10/20	0.44

▸	ALDH1A1	P00352	4/20	0.43

▸	RECQL	P46063	2/20	0.43

▸	HSD17B10	Q99714	2/20	0.43

▸	THRB	P10828	2/20	0.43

▸	HPGD	P15428	2/20	0.43

▸	CYP3A4	P08684	1/20	0.43

▸	ALOX15	P16050	1/20	0.43

▸	TSHR	P16473	1/20	0.43

▸	CASP1	P29466	1/20	0.43

▸	RAPGEF4	Q8WZA2	1/20	0.41

▸	PTGER4	P35408	1/20	0.39

▸	GAA	P10253	4/20	0.39

▸	MAPT	P10636	4/20	0.39

▸	KDM4E	B2RXH2	3/20	0.39

▸	NSD2	O96028	1/20	0.39

▸	POLB	P06746	1/20	0.39

▸	APEX1	P27695	1/20	0.39

▸	APOBEC3A	P31941	1/20	0.39

▸	CASP6	P55212	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sulfuric Acid SCHEMBL8107597	0.91	PRSS1 (0.50)	PRSS1ALDH1A1RECQLHSD17B10THRB
SCHEMBL2927441	0.91	PRSS1 (0.49)	PRSS1ALDH1A1RECQLHSD17B10THRB
Sulfuric Acid SCHEMBL8097992	0.88	PRSS1 (0.53)	PRSS1ALDH1A1RECQLHSD17B10THRB
Sulfuric Acid SCHEMBL11325766	0.85	ALDH1A1 (0.54)	ALDH1A1RECQLHSD17B10THRBHPGD
Sulfuric Acid SCHEMBL4626210	0.84	MAPT (0.43)	ALDH1A1RECQLHSD17B10THRBHPGD
Sulfuric Acid SCHEMBL10587043	0.83	RAPGEF4 (0.38)	ALDH1A1RECQLHSD17B10THRBHPGD
Sulfuric Acid SCHEMBL11060632	0.83	MAPT (0.42)	ALDH1A1RECQLHSD17B10THRBHPGD
Sulfuric Acid SCHEMBL31253929	0.83	RAPGEF4 (0.38)	ALDH1A1RECQLHSD17B10THRBHPGD
SCHEMBL6578153	0.82	RAPGEF4 (0.58)	ALDH1A1RECQLHSD17B10THRBHPGD
Sulfuric Acid SCHEMBL9680698	0.80	GAA (0.43)	ALDH1A1HSD17B10HPGDTSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20010005914-A1	OXIDATION DYES	ANDREAS J. BITTNER	2001-07-05	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20010005914-A1	OXIDATION DYES	AOC1, CBR3, KRT18	PRSS1 4608/4885ALDH1A1 26/4885RECQL 2228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.