Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999663 | 1.00 | POLB (0.56) | POLBALDH1A1MAPTGAANPC1 | |
| SCHEMBL16001849 | 0.87 | TAAR1 (0.51) | — | |
| SCHEMBL18734560 | 0.85 | MAPK1 (0.61) | POLBALDH1A1MAPTGAANPC1 | |
| SCHEMBL5451204 | 0.84 | MAPT (0.58) | POLBALDH1A1MAPTGAANPC1 | |
| SCHEMBL15883199 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK1L3MBTL1PKM | |
| SCHEMBL3191755 | 0.81 | MAPT (0.69) | POLBALDH1A1MAPTGAANPC1 | |
| SCHEMBL1921293 | 0.81 | RAPGEF4 (0.57) | POLBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL22140746 | 0.79 | MAPT (0.56) | POLBALDH1A1MAPTGAANPC1 | |
| SCHEMBL15489945 | 0.79 | POLB (0.54) | POLBALDH1A1MAPTGAANPC1 | |
| SCHEMBL5923798 | 0.79 | MAPT (0.67) | POLBALDH1A1MAPTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116653-B | Preparation method of pyrazole-triazole phosphine compound | 河北工业大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-111377964-B | Pyrazole-triazole phosphine compound and application thereof | 联化科技(上海)有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-111377964-A | Pyrazole-triazole phosphine compound and application thereof | 联化科技(上海)有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-111116653-A | Preparation method of pyrazole-triazole phosphine compound | 河北工业大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-1303525-B1 | PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2010-09-08 | — | — | EP | disclosed |