Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4800221 | 0.92 | RAPGEF4 (0.55) | RAPGEF4PTGS2ALDH1A1MAPTHTT | |
| SCHEMBL23193120 | 0.91 | PTGS2 (0.50) | RAPGEF4PTGS2ALDH1A1MAPTHTT | |
| SCHEMBL3946708 | 0.84 | ACHE (0.50) | RAPGEF4PTGS2ALDH1A1MAPTHTT | |
| SCHEMBL20916302 | 0.84 | MAPT (0.55) | RAPGEF4PTGS2ALDH1A1MAPTHTT | |
| SCHEMBL11332576 | 0.84 | PTGS2 (0.49) | RAPGEF4PTGS2ALDH1A1MAPTHTT | |
| SCHEMBL13800725 | 0.84 | PTGS2 (0.49) | RAPGEF4PTGS2ALDH1A1MAPTHTT | |
| SCHEMBL4144120 | 0.84 | ALDH1A1 (0.50) | RAPGEF4PTGS2ALDH1A1MAPTHTT | |
| SCHEMBL2927525 | 0.83 | ALDH1A1 (0.54) | RAPGEF4PTGS2ALDH1A1MAPTTSHR | |
| SCHEMBL5085672 | 0.83 | RAB9A (0.56) | RAPGEF4PTGS2ALDH1A1MAPTDHODH | |
| SCHEMBL2202005 | 0.82 | RAPGEF4 (0.55) | RAPGEF4PTGS2ALDH1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750897-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2020-12-16 | — | — | EP | disclosed |
| EP-1528074-B1 | NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | TOSOH CORP (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-8048833-B2 | Catalytic antioxidants | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-11-01 | — | — | US | disclosed |
| US-8048833-B2 | Catalytic antioxidants | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-11-01 | — | — | US | disclosed |
| US-20110230680-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110230680-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-09-22 | — | — | US | disclosed |
| US-7977286-B2 | Substituted N,N'-diaryl-m-phenylenediamines impart good levels of oxidation inhibition in lubricants, hydraulic fluids; lubricant is a synthetic oil derived from a Fischer-Tropsch wax via palladium/phosphine complex coupling catalyst; engine, industrial, marine, hydraulic, aviation, driveline oils | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-07-12 | — | — | US | disclosed |
| US-7977286-B2 | Substituted N,N'-diaryl-m-phenylenediamines impart good levels of oxidation inhibition in lubricants, hydraulic fluids; lubricant is a synthetic oil derived from a Fischer-Tropsch wax via palladium/phosphine complex coupling catalyst; engine, industrial, marine, hydraulic, aviation, driveline oils | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-07-12 | — | — | US | disclosed |
| EP-2327739-A1 | Novel triarylamine polymer, process for its production and its use | TOSOH CORPORATION (JP) | 2011-06-01 | — | — | EP | disclosed |
| US-7608680-B2 | Triarylamine polymer, process for producing the same, and use thereof | TOSOH CORPORATION (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20090048130-A1 | Catalytic antioxidants | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2009-02-19 | — | — | US | disclosed |
| US-20090048130-A1 | Catalytic antioxidants | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2009-02-19 | — | — | US | disclosed |
| WO-2007133462-A2 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-22 | — | — | WO | disclosed |
| US-20070265178-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2007-11-15 | — | — | US | disclosed |
| US-20070265178-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2007-11-15 | — | — | US | disclosed |
| US-20060241278-A1 | Novel triarylamine polymer, process for producing the same, and use thereof | TOSOH CORPORATION (JP) | 2006-10-26 | — | — | US | disclosed |
| US-20060017040-A9 | Novel triarylamine polymer, process for producing the same, and use thereof | SUZUKI TAKAO | 2006-01-26 | — | — | US | disclosed |
| EP-1528074-A1 | NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Tosoh Corporation (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-20040262574-A1 | Novel triarylamine polymer, process for producing the same, and use thereof | TOSOH CORPORATION (JP) | 2004-12-30 | — | — | US | disclosed |
| US-6034206-A | POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE | TOSOH CORPORATION (JP) | 2000-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265178-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | GPX4, SOD1, GPX1 | RAPGEF4 4264/4885PTGS2 1085/4885ALDH1A1 81/4885 |
| US-20110230680-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | GPX4, SOD1, GPX1 | RAPGEF4 4163/4885PTGS2 1192/4885ALDH1A1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.