Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18876129 | 0.84 | GRM2 (0.37) | GRM2PRKCI | |
| SCHEMBL18876176 | 0.76 | KDM4E (0.38) | GRM2MAOBPRKCI | |
| SCHEMBL21725647 | 0.74 | GRM2 (0.37) | GRM2MAOBPRKCI | |
| SCHEMBL18876179 | 0.70 | GRM2 (0.35) | GRM2PRKCI | |
| SCHEMBL18876187 | 0.70 | CYP19A1 (0.33) | GRM2PRKCI | |
| SCHEMBL25183109 | 0.69 | PRKCI (0.53) | MAOBPRKCI | |
| SCHEMBL27584224 | 0.68 | ADRA1A (0.37) | GRM2 | |
| SCHEMBL6427899 | 0.68 | GRM2 (0.32) | GRM2 | |
| SCHEMBL7920908 | 0.68 | TTR (0.44) | MAOB | |
| SCHEMBL837711 | 0.66 | PRMT5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |