Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829604 | 0.81 | MYC (0.40) | TTRTSHRTPMTMEN1KMT2A | |
| SCHEMBL7926725 | 0.80 | LMNA (0.40) | TTRTPMTMEN1KMT2AXDH | |
| SCHEMBL16597533 | 0.79 | KMO (0.55) | MAOBMEN1KMT2A | |
| SCHEMBL5068332 | 0.78 | CA12 (0.50) | TTRTSHRTPMT | |
| SCHEMBL30790881 | 0.76 | XDH (0.56) | MEN1KMT2AXDH | |
| SCHEMBL18876176 | 0.74 | KDM4E (0.38) | MAOBXDH | |
| SCHEMBL21725647 | 0.73 | GRM2 (0.37) | MAOBCYP2C9 | |
| SCHEMBL27580039 | 0.72 | MEN1 (0.45) | TSHRTPMTSRD5A2MEN1KMT2A | |
| SCHEMBL23306334 | 0.72 | XDH (0.38) | MAOBMEN1KMT2AXDHCYP2C9 | |
| SCHEMBL17277747 | 0.72 | TTR (0.43) | TTRTSHRMAOBTPMTSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |
| WO-2000006556-A1 | SUBSTITUTED OXAZOLINES AS ANTIPROLIFERATIVE AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | disclosed |