Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18893936 | 0.89 | LMNA (0.58) | SIGMAR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4658282 | 0.83 | ACHE (0.48) | SIGMAR1ALDH1A1LMNA | |
| SCHEMBL29245975 | 0.81 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL26071427 | 0.81 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1LMNAMC4R | |
| SCHEMBL1393167 | 0.81 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1LMNAMC4R | |
| SCHEMBL18893958 | 0.79 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1LMNA | |
| SCHEMBL65364 | 0.79 | SIGMAR1 (0.78) | SIGMAR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2974293 | 0.79 | SIGMAR1 (0.78) | SIGMAR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20719 | 0.79 | SIGMAR1 (0.78) | SIGMAR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14385456 | 0.78 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1LMNACYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304183-A | Five-membered and six-membered nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |