Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928276 | 0.91 | TDP1 (0.55) | L3MBTL1TDP1PTPN1GAACES2 | |
| SCHEMBL16807285 | 0.84 | L3MBTL1 (0.46) | L3MBTL1TDP1PTPN1GAACES2 | |
| SCHEMBL2927912 | 0.80 | L3MBTL1 (1.00) | L3MBTL1TDP1PTPN1CES2CES1 | |
| SCHEMBL11864426 | 0.80 | L3MBTL1 (0.68) | L3MBTL1TDP1PTPN1CES2CES1 | |
| SCHEMBL22917200 | 0.80 | GAA (0.50) | L3MBTL1TDP1GAACES2CES1 | |
| SCHEMBL17968495 | 0.80 | GAA (0.58) | L3MBTL1TDP1GAACES2CES1 | |
| SCHEMBL27819947 | 0.80 | GAA (0.50) | L3MBTL1TDP1GAACES2CES1 | |
| Methane SCHEMBL11867571 | 0.79 | L3MBTL1 (0.66) | L3MBTL1TDP1PTPN1CES2CES1 | |
| SCHEMBL16807287 | 0.78 | L3MBTL1 (0.77) | L3MBTL1TDP1PTPN1CES2CES1 | |
| SCHEMBL11000200 | 0.77 | CES2 (0.50) | GAACES2CES1HDAC4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303525-B1 | PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2010-09-08 | — | — | EP | disclosed |