Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927883 | 0.91 | L3MBTL1 (0.66) | TDP1L3MBTL1CES2CES1HIF1A | |
| SCHEMBL16807285 | 0.82 | L3MBTL1 (0.46) | TDP1L3MBTL1CES2CES1HIF1A | |
| SCHEMBL11000200 | 0.81 | CES2 (0.50) | CES2CES1HIF1AGAACNR2 | |
| SCHEMBL11750001 | 0.81 | CES2 (0.47) | TDP1L3MBTL1CES2CES1HIF1A | |
| SCHEMBL19926179 | 0.77 | CES2 (0.44) | TDP1L3MBTL1CES2CES1HIF1A | |
| SCHEMBL29874823 | 0.77 | CES2 (0.44) | TDP1L3MBTL1CES2CES1HIF1A | |
| SCHEMBL10779187 | 0.77 | LMNA (0.51) | TDP1L3MBTL1CES2CES1HIF1A | |
| SCHEMBL7589814 | 0.76 | TDP1 (0.55) | TDP1L3MBTL1CES2CES1GAA | |
| SCHEMBL29110200 | 0.75 | KMT2A (0.49) | TDP1L3MBTL1CES2CES1HIF1A | |
| SCHEMBL29831763 | 0.75 | HIF1A (0.43) | TDP1L3MBTL1CES2CES1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303525-B1 | PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2010-09-08 | — | — | EP | disclosed |