Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792514 | 1.00 | DRD2 (0.39) | DRD2HTR2AHTR6HTR7ALDH1A1 | |
| SCHEMBL30792515 | 0.94 | PTGS1 (0.44) | DRD2HTR2AHTR6HTR7ALDH1A1 | |
| SCHEMBL29279665 | 0.94 | PTGS1 (0.44) | DRD2HTR2AHTR6HTR7ALDH1A1 | |
| SCHEMBL13310458 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDKMT2ATHRB | |
| SCHEMBL2251832 | 0.80 | PTGS1 (0.54) | DRD2HTR2AHTR6HTR7ALDH1A1 | |
| Bromide SCHEMBL2590637 | 0.77 | DRD2 (0.50) | DRD2HTR2AHTR6HTR7ALDH1A1 | |
| SCHEMBL13310457 | 0.76 | PTGS1 (0.41) | DRD2HTR2AHTR6ALDH1A1KDM4E | |
| SCHEMBL801271 | 0.76 | DRD2 (0.49) | DRD2HTR2AHTR6HTR7ALDH1A1 | |
| SCHEMBL31069659 | 0.76 | DRD2 (0.49) | DRD2HTR2AHTR6HTR7ALDH1A1 | |
| SCHEMBL8739350 | 0.76 | DRD2 (0.49) | DRD2HTR2AHTR6HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659004-A | Phenothiazine polymerization inhibitor containing pyridoquinazolinone, and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-03-08 | — | — | CN | disclosed |