Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927438 | 0.98 | CYP1A2 (0.56) | CYP1A2ALDH1A1TLR4PPARGEPHX1 | |
| SCHEMBL30915401 | 0.98 | CYP1A2 (0.56) | CYP1A2ALDH1A1TLR4PPARGEPHX1 | |
| SCHEMBL31558673 | 0.98 | CYP1A2 (0.56) | CYP1A2ALDH1A1TLR4PPARGEPHX1 | |
| SCHEMBL30915400 | 0.98 | CYP1A2 (0.56) | CYP1A2ALDH1A1TLR4PPARGEPHX1 | |
| SCHEMBL2933689 | 0.98 | CYP1A2 (0.56) | CYP1A2ALDH1A1TLR4PPARGEPHX1 | |
| SCHEMBL30996494 | 0.95 | CYP1A2 (0.50) | CYP1A2TLR4PPARGCHRM2CHRM4 | |
| SCHEMBL2933925 | 0.89 | CYP1A2 (0.42) | CYP1A2ALDH1A1TLR4CHRM2CHRM4 | |
| SCHEMBL25198213 | 0.88 | CYP1A2 (0.53) | CYP1A2ALDH1A1PPARGEPHX1CHRM2 | |
| SCHEMBL20357429 | 0.88 | CYP1A2 (0.53) | CYP1A2ALDH1A1PPARGEPHX1CHRM2 | |
| SCHEMBL12200658 | 0.87 | CYP1A2 (0.39) | CYP1A2ALDH1A1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440608-B2 | Beta-substituted tetrandropyrana (on) s and method for the synthesis and the use thereof | V. MANE FILS (FR) | 2013-05-14 | — | — | US | claimed |
| EP-1773284-B1 | BETA-SUBSTITUTED TETRAHYDROPYRAN(ON)S AND METHOD FOR THE SYNTHESIS AND THEIR USE IN PERFUMERY | MANE FILS V (FR) | 2010-09-15 | — | — | EP | claimed |
| US-20080032914-A1 | Beta-Substituted Tetrahdropyrana (On) S And Method For The Synthesis And The Use Thereof | V. MANE FILS (FR) | 2008-02-07 | — | — | US | claimed |
| EP-1773284-A1 | BETA-SUBSTITUTED TETRAHYDROPYRAN(ON)S AND METHOD FOR THE SYNTHESIS AND THE USE THEREOF | V. Mane Fils (FR) | 2007-04-18 | — | — | EP | claimed |
| WO-2006021663-A1 | BETA-SUBSTITUTED TETRAHYDROPYRAN(ON)S AND METHOD FOR THE SYNTHESIS AND THE USE THEREOF | V. MANE FILS (FR) | 2006-03-02 | — | — | WO | claimed |
| EP-2206695-B1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2013-09-18 | — | — | EP | disclosed |
| US-8440608-B2 | Beta-substituted tetrandropyrana (on) s and method for the synthesis and the use thereof | V. MANE FILS (FR) | 2013-05-14 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-20100309402-A1 | FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-1773284-B1 | BETA-SUBSTITUTED TETRAHYDROPYRAN(ON)S AND METHOD FOR THE SYNTHESIS AND THEIR USE IN PERFUMERY | MANE FILS V (FR) | 2010-09-15 | — | — | EP | disclosed |
| EP-2206695-A1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |
| US-20080032914-A1 | Beta-Substituted Tetrahdropyrana (On) S And Method For The Synthesis And The Use Thereof | V. MANE FILS (FR) | 2008-02-07 | — | — | US | disclosed |
| EP-1773284-A1 | BETA-SUBSTITUTED TETRAHYDROPYRAN(ON)S AND METHOD FOR THE SYNTHESIS AND THE USE THEREOF | V. Mane Fils (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006021663-A1 | BETA-SUBSTITUTED TETRAHYDROPYRAN(ON)S AND METHOD FOR THE SYNTHESIS AND THE USE THEREOF | V. MANE FILS (FR) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100309402-A1 | FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | KIF23, HCN3, FZD7 | CYP1A2 2155/4885ALDH1A1 3844/4885TLR4 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.