Methane

Methane

SCHEMBL29280341

C.CC(C)(C)c1ccc(O)cc1O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
ALOX15 P16050 5/20 0.64
TYR P14679 4/20 0.64
LMNA P02545 3/20 0.64
HSD17B10 Q99714 2/20 0.64
NR1I2 O75469 1/20 0.64
CYP2C9 P11712 1/20 0.64
MIF P14174 1/20 0.64
HTT P42858 1/20 0.64
NFE2L2 Q16236 1/20 0.64
SMN1; SMN2 Q16637 3/20 0.56
KDM4E B2RXH2 1/20 0.56
CYP1A2 P05177 1/20 0.56
MAPT P10636 1/20 0.56
ATP2A2 P16615 1/20 0.56
ATP2A3 Q93084 1/20 0.56
TDP1 Q9NUW8 3/20 0.50
TSHR P16473 2/20 0.50
CA2 P00918 3/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL29280342 1.00 ALDH1A1 (0.64) ALDH1A1ALOX15TYRLMNAHSD17B10
SCHEMBL71137 0.98 ALDH1A1 (0.67) ALDH1A1ALOX15TYRLMNAHSD17B10
SCHEMBL30504082 0.98 ALDH1A1 (0.67) ALDH1A1ALOX15TYRLMNAHSD17B10
1,4-Dimethoxybenzene SCHEMBL28296591 0.84 ALDH1A1 (0.58) ALDH1A1ALOX15TYRLMNAHSD17B10
SCHEMBL278382 0.83 ALDH1A1 (0.54) ALDH1A1ALOX15TYRLMNAHSD17B10
SCHEMBL29375548 0.83 ALDH1A1 (0.54) ALDH1A1ALOX15TYRLMNAHSD17B10
SCHEMBL7949470 0.81 ALDH1A1 (0.52) ALDH1A1ALOX15TYRLMNAHSD17B10
Hydroquinone SCHEMBL23089046 0.80 ALDH1A1 (0.79) ALDH1A1ALOX15TYRLMNAHSD17B10
SCHEMBL2160202 0.80 ALDH1A1 (0.70) ALDH1A1ALOX15TYRLMNAHSD17B10
SCHEMBL31166944 0.79 TYR (0.50) ALDH1A1ALOX15TYRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117734266-A Extinction PS diffusion optical cladding plate and preparation method thereof 惠州市笨鸟先飞光学材料有限公司 2024-03-22 CN claimed
CN-117734266-A Extinction PS diffusion optical cladding plate and preparation method thereof 惠州市笨鸟先飞光学材料有限公司 2024-03-22 CN disclosed